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Clinical Chemistry

The leading international journal of laboratory medicine, Clinical Chemistry features nearly 400 peer-reviewed studies every year that help patients get accurate diagnoses and essential care, as well as recurring features like clinical case studies, perspectives, podcasts, and Q&A articles.
A female laboratory medicine professional adds a rack of tubes to a large shelf full of tubes.

About Clinical Chemistry

As the most trusted and authoritative journal in laboratory medicine, Clinical Chemistry strives to advance the field by showcasing vital research that holds the key to challenging patient health problems. The papers the journal publishes drive clinical testing forward and are chosen based on the novelty of their findings as well as the high quality of the scientific evidence they present.

ADLM Professional, Transitional, and Trainee members receive access to Clinical Chemistry as a free member benefit.

cholesterol as seen under a microscope in yellow and white circles

Low LDL-C estimation

The modified Sampson–NIH equation helps identify high-risk patients who could benefit from more intensive lipid-lowering therapy.

cholesterol as seen under a microscope in blue and green circles

Direct measurement of LDL-C

Modern LDL-C formulas outperform direct methods in patients with hypertriglyceridemia and low levels of LDL-C.

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Further Reading